Basic Information

IDDRAMP03329
SequenceLRDLVCYCRSRGCKGRERMNGTCRKGHLLYTLCCR
Length35
NameAlpha-defensin cryptdin-1 (Crp1; Rodents, mammals, animals)
SourceMus musculus (Mouse)
ActivityAntimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-
PathogenGram-positive bacterium: Listeria monocytogenes EGD;##Gram-negative bacteria: Escherichia coli ML-35p, mouse-avirulent Salmonella typhimurium 7953.
Hemolytic ActivityNo hemolysis information or data found in the reference(s) presented in this entry
CytotoxicityNo cytotoxicity information found
N-terminal ModificationFree
C-terminal ModificationFree
Linear/Cyclic/BranchedCyclic
Uniprot P11477, Q61448
PDB
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID1500431

Physicochemical Properties

Residues35
SequenceLRDLVCYCRSRGCKGRERMNGTCRKGHLLYTLCCR
Molecular Weight4121.912
Grand Average of Hydropathy-0.551
Isoelectric Point9.611
Charge at pH 7.46.438
Secondary StructureHelix: 0.229, Turn: 0.171, Sheet: 0.200
Instability Index16.851
Aromaticity0.057

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