Basic Information

IDDRAMP03332
SequenceLRGLLCYCRKGHCKRGERVRGTCGIRFLYCCPRR
Length34
NameAlpha-defensin cryptdin-4 (Defensin-related cryptdin4; Rodents, mammals, animals)
SourceMus musculus (Mouse)
ActivityAntimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-
PathogenGram-positive bacterium: Listeria monocytogenes EGD;##Gram-negative bacteria: Escherichia coli ML-35p, mouse-avirulent Salmonella typhimurium 7953.
Hemolytic ActivityNo hemolysis information or data found in the reference(s) presented in this entry
CytotoxicityNo cytotoxicity information found
N-terminal ModificationFree
C-terminal ModificationFree
Linear/Cyclic/BranchedCyclic
Uniprot P28311, A3KPC1, Q9QZL4
PDB 2GW9, 1TV0, 2GWP, 2LEW, 2LEY
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID15595831, 7927786, 16857681

Physicochemical Properties

Residues34
SequenceLRGLLCYCRKGHCKRGERVRGTCGIRFLYCCPRR
Molecular Weight4030.871
Grand Average of Hydropathy-0.462
Isoelectric Point10.134
Charge at pH 7.48.438
Secondary StructureHelix: 0.265, Turn: 0.176, Sheet: 0.147
Instability Index28.053
Aromaticity0.088

Similar Structure Search

Candidates based on structure

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