Basic Information

IDDRAMP03377
SequenceGLEYSQSFPGGEIAVCETCRLGRGKCRRTCIESEKIAGWCKLNFFCCRERI
Length51
NameBeta-defensin 12 (BD-12, mBD-12; Defensin, beta 12; Rodents, mammals, animals)
SourceMus musculus (Mouse)
ActivityAntimicrobial, Antibacterial
PathogenNo MICs found in DRAMP database
Hemolytic ActivityNo hemolysis information or data found in the reference(s) presented in this entry
CytotoxicityNot included yet
N-terminal ModificationNot included yet
C-terminal ModificationNot included yet
Linear/Cyclic/BranchedNot included yet
Uniprot Q8K4N3
PDB
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID12193721, 16141072, 14718547

Physicochemical Properties

Residues51
SequenceGLEYSQSFPGGEIAVCETCRLGRGKCRRTCIESEKIAGWCKLNFFCCRERI
Molecular Weight5805.72
Grand Average of Hydropathy-0.267
Isoelectric Point8.58
Charge at pH 7.42.382
Secondary StructureHelix: 0.255, Turn: 0.216, Sheet: 0.216
Instability Index50.904
Aromaticity0.098

Similar Structure Search

Candidates based on structure

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