Basic Information

IDDRAMP03512
SequenceWNPFKELEKVGQRVRDAVISAGPAVATVAQATALAK
Length36
NameCecropin-D (Cecropin D; Insects, animals)
SourceHyalophora cecropia (Cecropia moth)
ActivityAntimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-
PathogenGram-negative bacteria: Escherichia coli D21 (LC=0.43 µM), Escherichia coli D31 (LC=0.40 µM), Serratia marcescens Db11 (LC=14 µM), Serratia marcescens Db1108 (LC=12 µM), Serratia marcescens Db1121 (LC=12 µM), Strain 122 (LC=19 µM), Pseudomonas aeruginosa OT97 (LC=100 µM), Xenorhabdus nematophilus Xn21 (LC=19 µM);##Gram-positive bacteria: Bacillus megaterium Bmll (LC=41 µM), Bacillus subtilis Bs11 (LC>95 µM), B.thuringiensis Bt11 (LC>95 µM), Streptococcus fecalis AD-4 (LC>95 µM), Streptococcus fecalis DS16 (LC=88 µM), Micrococcus luteus M111 (LC=21 µM).
Hemolytic ActivityNo hemolysis information or data found in the reference(s) presented in this entry
CytotoxicityNot included yet
N-terminal ModificationNot included yet
C-terminal ModificationNot included yet
Linear/Cyclic/BranchedNot included yet
Uniprot P01510
PDB
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID7140755, 1711035

Physicochemical Properties

Residues36
SequenceWNPFKELEKVGQRVRDAVISAGPAVATVAQATALAK
Molecular Weight3793.333
Grand Average of Hydropathy0.042
Isoelectric Point9.697
Charge at pH 7.41.553
Secondary StructureHelix: 0.278, Turn: 0.167, Sheet: 0.333
Instability Index14.158
Aromaticity0.056

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