| ID | DRAMP03532 |
|---|---|
| Sequence | AKIPIKAIKTVGKAVGKGLRAINIASTANDVFNFLKPKKRKH |
| Length | 42 |
| Name | Moricin-1 (Insects, animals) |
| Source | Bombyx mori (Silk moth) |
| Activity | Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram- |
| Pathogen | Gram-negative bacteria: Escherichia coli JM109 (MIC=0.31 µM), Acinetobacter sp. NISL B-4653 (MIC=0.27 µM), Pseudomonas fluorescens IAM1179 (MIC=0.53 µM), Pseudomonas aeruginosa IAM15140 (MIC=0.81 µM);##Gram-positive bacteria: Bacillus subtilis IAM1107 (MIC=0.19 µM), Bacillus megaterium IAM1030 (MI=0.09 µM), Bacillus cereus IFO3457 (MIC=0.38 µM), Staphylococcus aureus ATCC6538P (MIC=0.21 µM), Staphylococcus aureus ATCC6538P (MIC=0.22 µM), Staphylococcus aureus IFO3083 (MIC=0.46 µM), Staphylococcus xylosus IAM1312 (MIC=0.27 µM), Staphylococcus epidermidis IFO12993 (MIC=0.18 µM), Streptococcus pyogenes ATCC21547 (MIC=0.25 µM). |
| Hemolytic Activity | No hemolysis information or data found in the reference(s) presented in this entry |
| Cytotoxicity | Not included yet |
| N-terminal Modification | Not included yet |
| C-terminal Modification | Not included yet |
| Linear/Cyclic/Branched | Not included yet |
| Uniprot | P82818 |
| PDB | 1KV4 |
| 3D View | |
| PDB Download | Download PDB Predicted by Alphafold2 |
| PubMed ID | 8530391, 11997013 |
Physicochemical Properties
| Residues | 42 |
|---|---|
| Sequence | AKIPIKAIKTVGKAVGKGLRAINIASTANDVFNFLKPKKRKH |
| Molecular Weight | 4543.453 |
| Grand Average of Hydropathy | -0.21 |
| Isoelectric Point | 11.363 |
| Charge at pH 7.4 | 9.622 |
| Secondary Structure | Helix: 0.286, Turn: 0.214, Sheet: 0.190 |
| Instability Index | 8.319 |
| Aromaticity | 0.048 |