Basic Information

IDDRAMP03642
SequenceGRKSDCFRKSGFCAFLKCPSLTLISGKCSRFYLCCKRIR
Length39
NameChicken heterophil peptides 1 (Antimicrobial peptide CHP1; Birds, animals)
SourceGallus gallus (Chicken)
ActivityAntimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal
PathogenGram-negative bacterium: Escherichia coli ATCC 25922 (MIC=2.7 µg/ml);##Gram-positive bacterium: Staphylococcus aureus (MIC=0.7 µg/ml).
Hemolytic ActivityNo hemolysis information or data found in the reference(s) presented in this entry
CytotoxicityNo cytotoxicity information found
N-terminal ModificationFree
C-terminal ModificationFree
Linear/Cyclic/BranchedCyclic
Uniprot P80389
PDB
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID7964174

Physicochemical Properties

Residues39
SequenceGRKSDCFRKSGFCAFLKCPSLTLISGKCSRFYLCCKRIR
Molecular Weight4480.401
Grand Average of Hydropathy-0.054
Isoelectric Point9.896
Charge at pH 7.48.396
Secondary StructureHelix: 0.282, Turn: 0.231, Sheet: 0.128
Instability Index36.923
Aromaticity0.128

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