| ID | DRAMP03714 |
|---|---|
| Sequence | FLGALWNVAKSVF |
| Length | 13 |
| Name | VmCT1 |
| Source | Vaejovis mexicanus smithi (Scorpion) |
| Activity | Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram- |
| Pathogen | [Ref.27912176] Gram-positive bacteria: Staphylococcus aureus ATCC 29213 (MIC=3.12 μmol/L), Bacillus subtilis ATCC 6633 (MIC=25μmol/L), Staphylococcus epidermidis ATCC 12228 (MIC=3.12μmol/L);##Gram-negative bacterium: Pseudomonas aeruginosa ATCC 27853 (MIC=0.78μmol/L), Escherichia coli D31 (MIC=3.12μmol/L), Serratia marcescens ATCC 4112 (MIC=1.56μmol/L), Enterobacter cloacae β-12 (MIC=25μmol/L), Micrococcus luteus A270 (MIC=1.56μmol/L);##Fungi: Candida albicans MDM8 (MIC=12.5μmol/L), Candida tropicalis IOC 4560 (MIC=6.25μmol/L), Candida parapsilosis IOC 4564 (MIC=25μmol/L), Aspergillus niger (MIC=25μmol/L), Cladosporium herbarum ATCC 26362 (MIC=50μmol/L), Cryptococcus neoformans (MIC=3.12μmol/L) |
| Hemolytic Activity | [Ref.27912176] 10% hemolysis at 1.99μmol/L against human red blood cells. |
| Cytotoxicity | Not included yet |
| N-terminal Modification | Not included yet |
| C-terminal Modification | Not included yet |
| Linear/Cyclic/Branched | Not included yet |
| Uniprot | I0DEB3 |
| PDB | |
| 3D View | |
| PDB Download | Download PDB Predicted by Alphafold2 |
| PubMed ID | 27912176 |
Physicochemical Properties
| Residues | 13 |
|---|---|
| Sequence | FLGALWNVAKSVF |
| Molecular Weight | 1451.709 |
| Grand Average of Hydropathy | 1.208 |
| Isoelectric Point | 8.75 |
| Charge at pH 7.4 | 0.555 |
| Secondary Structure | Helix: 0.538, Turn: 0.231, Sheet: 0.308 |
| Instability Index | 30.408 |
| Aromaticity | 0.231 |
