| ID | DRAMP03896 |
|---|---|
| Sequence | FKCRRWQWRMKALGA |
| Length | 15 |
| Name | LFB A12 (derivative of LFB, residue substitution with alanine at position 12) |
| Source | Synthetic construct |
| Activity | Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram- |
| Pathogen | Gram-negative bacterium: Escherichia coli (MIC=25 µM);##Gram-positive bacterium: Staphylococcus aureus (MIC>100 µM). |
| Hemolytic Activity | No hemolysis information or data found in the reference(s) presented in this entry |
| Cytotoxicity | Not included yet |
| N-terminal Modification | Not included yet |
| C-terminal Modification | Not included yet |
| Linear/Cyclic/Branched | Not included yet |
| Uniprot | |
| PDB | |
| 3D View | |
| PDB Download | Download PDB Predicted by Alphafold2 |
| PubMed ID | 11095180 |
Physicochemical Properties
| Residues | 15 |
|---|---|
| Sequence | FKCRRWQWRMKALGA |
| Molecular Weight | 1937.343 |
| Grand Average of Hydropathy | -0.827 |
| Isoelectric Point | 11.724 |
| Charge at pH 7.4 | 4.528 |
| Secondary Structure | Helix: 0.267, Turn: 0.067, Sheet: 0.267 |
| Instability Index | 70.027 |
| Aromaticity | 0.2 |