| ID | DRAMP04032 |
|---|---|
| Sequence | ALRLAIRKR |
| Length | 9 |
| Name | Modified defensin |
| Source | Synthetic construct |
| Activity | Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram- |
| Pathogen | Gram-positive bacteria: Staphylococcus aureus (MIC=5 µg/ml), Staphylococcus aureus (MRSA) (MIC>48 µg/ml);##Gram-negative bacteria: Escherichia coli (MIC=4 µg/ml), Pseudomonas aeruginosa (MIC=15 µg/ml). |
| Hemolytic Activity | No hemolysis information or data found in the reference(s) presented in this entry |
| Cytotoxicity | Not included yet |
| N-terminal Modification | Not included yet |
| C-terminal Modification | Not included yet |
| Linear/Cyclic/Branched | Not included yet |
| Uniprot | |
| PDB | |
| 3D View | |
| PDB Download | Download PDB Predicted by Alphafold2 |
| PubMed ID | 10561605 |
Physicochemical Properties
| Residues | 9 |
|---|---|
| Sequence | ALRLAIRKR |
| Molecular Weight | 1096.373 |
| Grand Average of Hydropathy | -0.189 |
| Isoelectric Point | 12 |
| Charge at pH 7.4 | 3.605 |
| Secondary Structure | Helix: 0.333, Turn: 0.000, Sheet: 0.444 |
| Instability Index | 66.511 |
| Aromaticity | 0 |