| ID | DRAMP04035 |
|---|---|
| Sequence | ALYLAIRKR |
| Length | 9 |
| Name | Modified defensin |
| Source | Synthetic construct |
| Activity | Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram- |
| Pathogen | Gram-positive bacteria: Staphylococcus aureus (MIC=3 µg/ml), Staphylococcus aureus (MRSA) (MIC=30 µg/ml);##Gram-negative bacteria: Escherichia coli (MIC=4 µg/ml), Pseudomonas aeruginosa (MIC=4 µg/ml). |
| Hemolytic Activity | No hemolysis information or data found in the reference(s) presented in this entry |
| Cytotoxicity | Not included yet |
| N-terminal Modification | Not included yet |
| C-terminal Modification | Not included yet |
| Linear/Cyclic/Branched | Not included yet |
| Uniprot | |
| PDB | |
| 3D View | |
| PDB Download | Download PDB Predicted by Alphafold2 |
| PubMed ID | 10561605 |
Physicochemical Properties
| Residues | 9 |
|---|---|
| Sequence | ALYLAIRKR |
| Molecular Weight | 1103.361 |
| Grand Average of Hydropathy | 0.167 |
| Isoelectric Point | 11.001 |
| Charge at pH 7.4 | 2.603 |
| Secondary Structure | Helix: 0.444, Turn: 0.000, Sheet: 0.444 |
| Instability Index | 45.111 |
| Aromaticity | 0.111 |