Basic Information

IDDRAMP02778
SequenceAHCLAIGRK
Length9
NameDefensin (Insects, animals)
SourceOryctes rhinoceros (Coconut rhinoceros beetle)
ActivityAntimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-
Pathogen[Ref.10561605] Gram-positive bacteria: Staphylococcus aureus (MIC=25 µg/ml), Staphylococcus aureus (MRSA) (MIC>50 µg/ml);## Gram-negative bacteria: Escherichia coli (MIC=25 µg/ml), Pseudomonas aeruginosa (MIC>50 µg/ml).
Hemolytic Activity[Ref.10561605] Had no hemolytic activity against rabbit erythrocytes
CytotoxicityNot included yet
N-terminal ModificationNot included yet
C-terminal ModificationNot included yet
Linear/Cyclic/BranchedNot included yet
Uniprot O96049
PDB
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID10561605

Physicochemical Properties

Residues9
SequenceAHCLAIGRK
Molecular Weight968.178
Grand Average of Hydropathy0.267
Isoelectric Point9.511
Charge at pH 7.41.617
Secondary StructureHelix: 0.222, Turn: 0.111, Sheet: 0.333
Instability Index20.856
Aromaticity0

Similar Structure Search

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