Basic Information

IDDRAMP21223
SequenceILKKIWKpIKKLF
Length13
NameIsCT-p (Derived from IsCT-P)
SourceSynthetic construct
ActivityAntimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-
Pathogen[Ref.16040002] Gram-positive bacteria : Staphylococcus aureus(KCTC 1621)(MIC=1 μM), MRSA (CCARM 3001)(MIC=2 μM), MRSA (CCARM 3543)(MIC=1 μM), Bacillus subtilis(KCTC 3068)(MIC=2 μM), Staphylococcus epidermidis(KCTC 1917)(MIC=1 μM);##Gram-negative bacteria : Escherichia coli(KCTC 1682)(MIC=2 μM), Pseudomonas aeruginosa(KCTC 1637)(MIC=2 μM), MDRPA (CCARM 2095)(MIC=2 μM), Salmonella typhimurium(KCTC 1926)(MIC=2 μM)
Hemolytic Activity[Ref.16040002] 0% hemolysis at 200 μM against human red blood cells
Cytotoxicity[Ref.16040002] No cytotoxicity information found
N-terminal ModificationFree
C-terminal ModificationAmidation
Linear/Cyclic/BranchedLinear
Uniprot
PDB
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID16040002

Physicochemical Properties

Residues13
SequenceILKKIWKpIKKLF
Molecular Weight1655.164
Grand Average of Hydropathy0.146
Isoelectric Point10.602
Charge at pH 7.44.545
Secondary StructureHelix: 0.538, Turn: 0.077, Sheet: 0.154
Instability Index-7.877
Aromaticity0.154

Similar Structure Search

Candidates based on structure

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