Basic Information

IDDRAMP03928
SequenceKWKLFKKAVLKVLTT
Length15
NameCecropin A (1-7)-melittin (4-11)hybrid peptide (CAM)
SourceSynthetic construct
ActivityAntimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-
PathogenGram-negative bacteria: Escherichia coli D21 (MIC=0.6 µM), Pseudomonas aeruginosa OT97 (MIC=4 µM);##Gram-positive bacteria: Bacillus subtilis Bs11 (MIC=0.6 µM), Bacillus megaterium Bm11 (MIC=0.5 µM), Staphylococcus aureus Cowan 1 (MIC=8 µM), Streptococcus pyogenes (MIC=0.7 µM).
Hemolytic ActivityNo hemolysis information or data found in the reference(s) presented in this entry
CytotoxicityNot included yet
N-terminal ModificationNot included yet
C-terminal ModificationNot included yet
Linear/Cyclic/BranchedNot included yet
Uniprot
PDB
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID1733777, 20111863

Physicochemical Properties

Residues15
SequenceKWKLFKKAVLKVLTT
Molecular Weight1803.281
Grand Average of Hydropathy0.173
Isoelectric Point10.602
Charge at pH 7.44.545
Secondary StructureHelix: 0.467, Turn: 0.000, Sheet: 0.267
Instability Index-17.667
Aromaticity0.133

Similar Structure Search

Candidates based on structure

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