Basic Information
| ID | DRAMP20989 |
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| Sequence | wFKKlLKkAlrLWKkVL |
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| Length | 17 |
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| Name | CPF-8 (Derived from CPF-C1) |
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| Source | Synthetic construct |
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| Activity | Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram- |
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| Pathogen | [Ref.28371431]Gram-positive bacteria : Staphylococcuss aureus ATCC 25923 (MIC=8 μg/ml), Staphylococcuss aureus 725 (MIC=8 μg/ml), Staphylococcuss aureus 794 (MIC=8 μg/ml), Staphylococcuss aureus 936 (MIC=8 μg/ml);##Gram-negative bacteria : Escherichia coli ATCC 25922 (MIC=8 μg/ml), Escherichia coli 780 (MIC=8 μg/ml), Escherichia coli 804 (MIC=8 μg/ml), Escherichia coli 850 (MIC=8 μg/ml), Pseudomonas aeruginosa ATCC 27853 (MIC=8 μg/ml), Pseudomonas aeruginosa 2760 (MIC=8 μg/ml), Pseudomonas aeruginosa 9132 (MIC=8 μg/ml), Acinetobacter baumannii ATCC 19606 (MIC=8 μg/ml), Acinetobacter baumannii 1980 (MIC=8 μg/ml), Acinetobacter baumannii 2982 (MIC=8 μg/ml), Acinetobacter baumannii 4956 (MIC=8 μg/ml) |
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| Hemolytic Activity | [Ref.28371431]13% hemolysis at 4 μg/ml , 5% hemolysis at 8 μg/ml , 0% hemolysis at 16 μg/ml , 0% hemolysis at 32 μg/ml , 0% hemolysis at 64 μg/ml , 0% hemolysis at 128 μg/ml , 0% hemolysis at 256 μg/ml , 0% hemolysis at 512 μg/ml against human red blood cells |
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| Cytotoxicity | [Ref.28371431] No cytotoxicity information found |
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| N-terminal Modification | Free |
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| C-terminal Modification | Amidation |
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| Linear/Cyclic/Branched | Linear |
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| Uniprot |
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| PDB |
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| 3D View | |
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| PDB Download | Download PDB Predicted by Alphafold2 |
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| PubMed ID | 28371431 |
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