| ID | DRAMP04664 |
|---|---|
| Sequence | AKRLKKLAKKIWKWK |
| Length | 15 |
| Name | HPA3NT3-A2 (HPA3NT3 peptide analogs) |
| Source | Helicobacter pylori |
| Activity | Antimicrobial, Antibacterial, Anti-gram+, Anti-gram-, Antifungal |
| Pathogen | [Ref.22982494] Gram-positive bacteria : Staphylococcus aureus(MIC=4 μM), Listeria monocytogenes(MIC=2 μM), Staphylococcus epidermidis(MIC=2-4 μM), Bacillus subtilis(MIC=2 μM);##Gram-negative bacteria : Escherichia coli(MIC=4 μM), Pseudomonas aeruginosa(MIC=2 μM), Primula vulgaris(MIC=2-4 μM), Salmonella typhimurium(MIC=2 μM);##Fungi : Candida albicans(MIC=8 μM), Trichosporon beigelii(MIC=16 μM), Aspergillus awamori(MIC=8 μM), Aspergillus flavus(MIC=8 μM), Aspergillus fumigatus(MIC=4 μM), Aspergillus parasiticus(MIC=8 μM) |
| Hemolytic Activity | [Ref.22982494] 0% hemolysis at 250 μM against human red blood cells |
| Cytotoxicity | Not included yet |
| N-terminal Modification | Not included yet |
| C-terminal Modification | Not included yet |
| Linear/Cyclic/Branched | Not included yet |
| Uniprot | |
| PDB | |
| 3D View | |
| PDB Download | Download PDB Predicted by Alphafold2 |
| PubMed ID | 22982494 |
Physicochemical Properties
| Residues | 15 |
|---|---|
| Sequence | AKRLKKLAKKIWKWK |
| Molecular Weight | 1925.456 |
| Grand Average of Hydropathy | -1.193 |
| Isoelectric Point | 11.472 |
| Charge at pH 7.4 | 7.59 |
| Secondary Structure | Helix: 0.333, Turn: 0.000, Sheet: 0.267 |
| Instability Index | 14.087 |
| Aromaticity | 0.133 |