Basic Information

IDDRAMP18395
SequenceFFGHLFRGIINVGKHIHGLLSG
Length22
NamemoroPC-NH2 (moronecidin-like peptide; fish, animals)
SourceParachaenichthys charcoti
ActivityAntimicrobial, Antibacterial, Antifungal
PathogenActive against Gram- E. cloacae ATCC 13047 (MIC 25 uM), S. sonnei (ATCC 29930) (MIC 5 uM), Psychrobacter sp. (PAMC 25501) (MIC 2.5 uM), E. coli DH5alpha (MIC 5 uM), Gram+ E. faecalis (ATCC 29212) (MIC 25 uM), S. pyogenes (ATCC 19615) (MIC 2.5 uM), S. aureus (ATCC 33591), L. monocytogenes (ATCC 15313) (MIC 5 uM), and yeast C. tropicalis (ATCC 20115) (MIC 5 uM).
Hemolytic ActivityNo hemolysis information or data found in the reference(s) presented in this entry
Cytotoxicity[Ref.28122029]No cytotoxicity information found
N-terminal ModificationFree
C-terminal ModificationAmidation
Linear/Cyclic/BranchedLinear
Uniprot
PDB
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID28122029

Physicochemical Properties

Residues22
SequenceFFGHLFRGIINVGKHIHGLLSG
Molecular Weight2419.826
Grand Average of Hydropathy0.6
Isoelectric Point11.001
Charge at pH 7.41.665
Secondary StructureHelix: 0.455, Turn: 0.318, Sheet: 0.136
Instability Index14.977
Aromaticity0.136

Similar Structure Search

Candidates based on structure

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