Basic Information

IDDRAMP18505
SequenceGLFDIIKKIAESFKFSEAIKKIIDFLG
Length27
Name(AU)2K (Aurein 1.2 peptide derivative)
SourceLitoria raniformis (Southern bell frog)
ActivityAntimicrobial, Antibacterial, Anti-Gram-
Pathogen[Ref.23519707]Gram-negative bacterium: Escherichia coli (MIC=128 μmol/L)
Hemolytic Activity[Ref.23519707]~30% hemolysis at 32μmol/L, 10% hemolysis at 4 μmol/L against human red blood cells.
CytotoxicityNot included yet
N-terminal ModificationNot included yet
C-terminal ModificationNot included yet
Linear/Cyclic/BranchedNot included yet
Uniprot
PDB
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PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID23519707

Physicochemical Properties

Residues27
SequenceGLFDIIKKIAESFKFSEAIKKIIDFLG
Molecular Weight3071.649
Grand Average of Hydropathy0.5
Isoelectric Point8.379
Charge at pH 7.40.548
Secondary StructureHelix: 0.444, Turn: 0.148, Sheet: 0.222
Instability Index7.53
Aromaticity0.148

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