| ID | DRAMP18510 |
|---|---|
| Sequence | KKLALLALKKWLLALKKLALLALKK |
| Length | 25 |
| Name | D-LAK120 |
| Source | Synthetic construct |
| Activity | Antimicrobial, Antibacterial, Anti-Gram-, Antiplasmodial |
| Pathogen | [Ref.22869378]Gram-negative bacteria: Escherichia coli NCTC 9001 (MIC=1.48±0.53 μM), Escherichia coli Top 10 (MIC=0.62±0.15 μM), Pseudomonas aeruginosa (MIC=2.71±1.07 μM);##Plasmodium: Plasmodium falciparum 3D7 (EC50=1.95±0.08 μM) |
| Hemolytic Activity | [Ref.22869378]HC50=4.06±1.30 μM against Not found (The literature does not mention) |
| Cytotoxicity | Not included yet |
| N-terminal Modification | Not included yet |
| C-terminal Modification | Not included yet |
| Linear/Cyclic/Branched | Not included yet |
| Uniprot | |
| PDB | |
| 3D View | |
| PDB Download | Download PDB Predicted by Alphafold2 |
| PubMed ID | 22869378 |
Physicochemical Properties
| Residues | 25 |
|---|---|
| Sequence | KKLALLALKKWLLALKKLALLALKK |
| Molecular Weight | 2829.727 |
| Grand Average of Hydropathy | 0.748 |
| Isoelectric Point | 10.845 |
| Charge at pH 7.4 | 7.537 |
| Secondary Structure | Helix: 0.480, Turn: 0.000, Sheet: 0.640 |
| Instability Index | -2.444 |
| Aromaticity | 0.04 |