Basic Information

IDDRAMP18538
SequenceKWKSFLKTFKSAVKTVLHTALKAISS
Length26
NameV681
SourceSynthetic construct
ActivityAntimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-
Pathogen[Ref.15677462]Gram-positive bacteria: Staphylococcus aureus 25923 (MIC=16.0 μg/ml), Staphylococcus aureus SAP0017 (MIC=9.0 μg/ml), Staphylococcus epidermidis C621 (MIC=5.0 μg/ml), Bacillus subtilis C971 (MIC=2.2 μg/ml), Enterococcus faecalis C625 (MIC=16.0 μg/ml), Corynebacterium xerosis C875 (MIC=2.5 μg/ml), The geometric mean of MIC values above six Gram-positive strains (MIC=6.3 μg/ml);##Gram-negative bacteria: Escherichia coli UB1005 (MIC=7.1 μg/ml), Escherichia coli DC2 (MIC=4.5 μg/ml), Salmonella typhimurium C587 (MIC=20.2 μg/ml), Salmonella typhimurium C610 (MIC=5.7 μg/ml), Pseudomonas aeruginosa H187 (MIC=6.4 μg/ml), Pseudomonas aeruginosa H188 (MIC=20.2 μg/ml), The geometric mean of MIC values above six Gram-negative strains (MIC=8.8 μg/ml)
Hemolytic Activity[Ref.15677462]MHC=15.6 μg/ml against human red blood cells
CytotoxicityNot included yet
N-terminal ModificationNot included yet
C-terminal ModificationNot included yet
Linear/Cyclic/BranchedNot included yet
Uniprot
PDB
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID15677462

Physicochemical Properties

Residues26
SequenceKWKSFLKTFKSAVKTVLHTALKAISS
Molecular Weight2920.493
Grand Average of Hydropathy0.096
Isoelectric Point10.699
Charge at pH 7.45.579
Secondary StructureHelix: 0.346, Turn: 0.154, Sheet: 0.231
Instability Index5.45
Aromaticity0.115

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