| ID | DRAMP18564 |
|---|---|
| Sequence | KWLRRVWRWWR |
| Length | 11 |
| Name | MAP-04-03 (Ixosin-B peptide derivative) |
| Source | Synthetic construct |
| Activity | Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram- |
| Pathogen | [Ref.22578463]Gram-positive bacterium: Staphylococcus aureus (MIC90=2.5 μM);##Gram-negative bacterium: Escherichia coli (MIC90=15 μM), Pseudomonas aeroginosa (MIC90=20 μM) |
| Hemolytic Activity | [Ref.22578463]100% hemolysis at 100μM against human red blood cells |
| Cytotoxicity | Not included yet |
| N-terminal Modification | Not included yet |
| C-terminal Modification | Not included yet |
| Linear/Cyclic/Branched | Not included yet |
| Uniprot | |
| PDB | |
| 3D View | |
| PDB Download | Download PDB Predicted by Alphafold2 |
| PubMed ID | 22578463 |
Physicochemical Properties
| Residues | 11 |
|---|---|
| Sequence | KWLRRVWRWWR |
| Molecular Weight | 1728.059 |
| Grand Average of Hydropathy | -1.591 |
| Isoelectric Point | 12 |
| Charge at pH 7.4 | 4.555 |
| Secondary Structure | Helix: 0.545, Turn: 0.000, Sheet: 0.091 |
| Instability Index | 141.964 |
| Aromaticity | 0.364 |