Basic Information

IDDRAMP18569
SequenceVNSKKISGKSIKVSK
Length15
NameLL-IIIs-4 (lasioglossin III peptide derivative)
SourceSynthetic construct
ActivityAntimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-
Pathogen[Ref.22526241]Gram-positive bacteria: Micrococcus luteus (MIC=2 μM), Bacillus cereus (MIC=1.1 μM), Staphylococcus aureus (MIC=80 μM);##Gram-negative bacteria: Escherichia coli (MIC=20 μM).
Hemolytic Activity[Ref.22526241]LC50>100 μM against human red blood cells
CytotoxicityNot included yet
N-terminal ModificationNot included yet
C-terminal ModificationNot included yet
Linear/Cyclic/BranchedNot included yet
Uniprot
PDB
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PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID22526241

Physicochemical Properties

Residues15
SequenceVNSKKISGKSIKVSK
Molecular Weight1602.917
Grand Average of Hydropathy-0.613
Isoelectric Point10.602
Charge at pH 7.44.511
Secondary StructureHelix: 0.267, Turn: 0.400, Sheet: 0.000
Instability Index-13.307
Aromaticity0

Similar Structure Search

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