| ID | DRAMP18570 |
|---|---|
| Sequence | VNRKKILGKSIKVVK |
| Length | 15 |
| Name | LL-IIIs-5 cis (lasioglossin III peptide derivative) |
| Source | Synthetic construct |
| Activity | Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram- |
| Pathogen | [Ref.22526241]Gram-positive bacteria: Micrococcus luteus (MIC=0.9 μM), Bacillus cereus (MIC=0.9 μM), Staphylococcus aureus (MIC=45 μM);##Gram-negative bacteria: Escherichia coli (MIC=3.5 μM), Pseudomonas aeruginosa (MIC=80 μM). |
| Hemolytic Activity | [Ref.22526241]LC50=100 μM against human red blood cells |
| Cytotoxicity | Not included yet |
| N-terminal Modification | Not included yet |
| C-terminal Modification | Not included yet |
| Linear/Cyclic/Branched | Not included yet |
| Uniprot | |
| PDB | |
| 3D View | |
| PDB Download | Download PDB Predicted by Alphafold2 |
| PubMed ID | 22526241 |
Physicochemical Properties
| Residues | 15 |
|---|---|
| Sequence | VNRKKILGKSIKVVK |
| Molecular Weight | 1710.159 |
| Grand Average of Hydropathy | -0.22 |
| Isoelectric Point | 11.388 |
| Charge at pH 7.4 | 5.511 |
| Secondary Structure | Helix: 0.400, Turn: 0.200, Sheet: 0.067 |
| Instability Index | -2.387 |
| Aromaticity | 0 |