Basic Information

IDDRAMP18631
SequenceVGHNADLQIKLSIRRLLAAGVLKQTKGVGA
Length30
NameH5(61–90) V1 (Histone H5 peptide derivative)
SourceSynthetic construct
ActivityAntimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-
Pathogen[Ref.29402952] Gram-positive bacteria: Listeria monocytogenes (MIC=23.1±8.1 μg/mL);##Gram-negative bacterium: Pseudomonas aeruginosa (MIC=16±0 μg/mL)
Hemolytic ActivityNo hemolysis information or data found in the reference(s) presented in this entry
CytotoxicityNot included yet
N-terminal ModificationNot included yet
C-terminal ModificationNot included yet
Linear/Cyclic/BranchedNot included yet
Uniprot
PDB
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID29402952

Physicochemical Properties

Residues30
SequenceVGHNADLQIKLSIRRLLAAGVLKQTKGVGA
Molecular Weight3127.685
Grand Average of Hydropathy0.227
Isoelectric Point11.097
Charge at pH 7.43.553
Secondary StructureHelix: 0.333, Turn: 0.200, Sheet: 0.300
Instability Index32.76
Aromaticity0

Similar Structure Search

Candidates based on structure

Address: No.2699 Qianjin Street, Changchun City, China. Zip Code: 130012. 苏ICP备2021057230号-1.