Basic Information

IDDRAMP18698
SequenceAERVGAGAPVYL
Length12
NameHistone H2A (Trouts, fish, animals)
SourceOncorhynchus mykiss (Rainbow trout) (Salmo gairdneri)
ActivityAntimicrobial, Antibacterial, Anti-Gram+, Antifungal
Pathogen[Ref.12164782] Gram positive bacteria: Aerococcus viridans (MIC=0.08-0.15 µM), Bacillus subtilis (MIC=0.6-1.2 µM), Micrococcus luteus (MIC=0.6-1.2 µM), Planococcus citreus (MIC=0.08-0.15 µM), Renibacterium salmoninarum (MIC=0.15-0.3 µM);##Fungi: Saccharomyces cerevisiae (MIC=0.3-0.6 µM).
Hemolytic ActivityNo hemolysis information or data found in the reference(s) presented in this entry
CytotoxicityNot included yet
N-terminal ModificationNot included yet
C-terminal ModificationNot included yet
Linear/Cyclic/BranchedNot included yet
Uniprot P02264
PDB
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID12164782

Physicochemical Properties

Residues12
SequenceAERVGAGAPVYL
Molecular Weight1202.359
Grand Average of Hydropathy0.492
Isoelectric Point6.046
Charge at pH 7.4-0.394
Secondary StructureHelix: 0.333, Turn: 0.250, Sheet: 0.417
Instability Index13.758
Aromaticity0.083

Similar Structure Search

Candidates based on structure

Address: No.2699 Qianjin Street, Changchun City, China. Zip Code: 130012. 苏ICP备2021057230号-1.