Basic Information
| ID | DRAMP20804 |
|---|
| Sequence | DLRDSWKVIGSDKK |
|---|
| Length | 14 |
|---|
| Name | AI-hemocidins 2 (Hb-1 truncated peptide) |
|---|
| Source | Arca inflata |
|---|
| Activity | Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram- |
|---|
| Pathogen | [Ref.28661457] Gram-negative bacteria: Escherichia coli ATCC 25922 (MIC=45.54 μM), Pseudomonas aeruginosa ATCC 27853 (MIC=91.08 μM), Pseudomonas aeruginosa clinical isolate (MIC=91.08 μM);##Gram-positive bacteria: Staphylococcus aureus ATCC 25923 (MIC=22.77 μM), Bacillus subtilis ATCC 6633 (MIC=182.16 μM). |
|---|
| Hemolytic Activity | [Ref.28661457] 10.27 ± 0.42% hemolysis at 500 μg/mL against murine red blood cells. |
|---|
| Cytotoxicity | [Ref.28661457] The cell viability of HEK293 at the peptide concentration of 250 μg/ml is 88.18±9.48%. IC50 > 1000 μg/ml against HEK293 cells. |
|---|
| N-terminal Modification | Free |
|---|
| C-terminal Modification | Free |
|---|
| Linear/Cyclic/Branched | Linear |
|---|
| Uniprot |
|
|---|
| PDB |
|
|---|
| 3D View | |
|---|
| PDB Download | Download PDB Predicted by Alphafold2 |
|---|
| PubMed ID | 28661457 |
|---|
