| ID | DRAMP20820 |
|---|---|
| Sequence | FRIRVRV |
| Length | 7 |
| Name | FV7 |
| Source | Synthetic construct |
| Activity | Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram- |
| Pathogen | [Ref.28178190] Gram-positive bacteria: Staphylococcus aureus ATCC 29213 (MIC=64 μM), Streptococcus Faecalis ATCC 29212 (MIC=32 μM), Bacillus subtilis CMCC 63501 (MIC=16 μM), Staphylococcus epidermidis ATCC 12228 (MIC=32 μM);##Gram-negative bacteria: Escherichia coli ATCC 25922 (MIC=16 μM), Escherichia coli UB 1005 (MIC=32 μM), Pseudomonas aeruginosa ATCC 27853 (MIC=16 μM), Pseudomonas aeruginosa PAO1 (MIC=32 μM), Salmonella typhimurium ATCC 14028 (MIC=16 μM), Salmonella typhimurium ATCC 7731 (MIC=32 μM). |
| Hemolytic Activity | [Ref.28178190] 3% hemolysis at 128 μM against human red cells |
| Cytotoxicity | [Ref.28178190] No cytotoxicity information found |
| N-terminal Modification | Free |
| C-terminal Modification | Amidation |
| Linear/Cyclic/Branched | Linear |
| Uniprot | |
| PDB | |
| 3D View | |
| PDB Download | Download PDB Predicted by Alphafold2 |
| PubMed ID | 28178190 |
Physicochemical Properties
| Residues | 7 |
|---|---|
| Sequence | FRIRVRV |
| Molecular Weight | 945.166 |
| Grand Average of Hydropathy | 0.314 |
| Isoelectric Point | 12 |
| Charge at pH 7.4 | 2.557 |
| Secondary Structure | Helix: 0.571, Turn: 0.000, Sheet: 0.000 |
| Instability Index | 8.571 |
| Aromaticity | 0.143 |
