Basic Information
| ID | DRAMP03603 |
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| Sequence | ARLKKCFNKVTGYCRKKCKVGERYEIGCLSGKLCCAN |
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| Length | 37 |
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| Name | Human beta-defensin 28 (hBD-28; hBD28; Human, mammals, animals) |
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| Source | Homo sapiens (Human) |
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| Activity | Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram- |
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| Pathogen | Gram-negative bacteria: Escherichia coli DSM1103 (MIC=37.5 µg/ml), Klebsiella pneumoniae DSM681 (MIC=50 µg/ml), Pseudomonas aeruginosa DSM1128 (MIC=37.5 µg/ml);##Gram-positive bacteria: Staphylococcus aureus ATCC25923 (MIC=25 µg/ml), Streptococcus pneumoniae DSM11865 (MIC=37.5 µg/ml). |
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| Hemolytic Activity | [Ref.15625724] It is slightly hemolytic (<12%) against human erythrocytes at the highest concentration of 500 μg/ml. |
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| Cytotoxicity | No cytotoxicity information found |
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| N-terminal Modification | Free |
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| C-terminal Modification | Free |
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| Linear/Cyclic/Branched | Cyclic |
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| Uniprot |
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| PDB |
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| 3D View | |
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| PDB Download | Download PDB Predicted by Alphafold2 |
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| PubMed ID | 15625724 |
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