Basic Information

IDDRAMP20870
SequenceGLLKRIKT
Length8
NamePal-ano-8 (Pal-anoplin peptide derivative)
SourceSynthetic construct
ActivityAntimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal
Pathogen[Ref.29614317] Gram-positive bacteria: Staphylococcus aureus ATCC 25923 (MIC=1.63 μg/mL);##Gram-negative bacteria: Escherichia coli ATCC 25922 (MIC=3.25 μg/mL);##Fungi: Candida albicans ATCC 10231 (MIC=26 μg/mL).
Hemolytic Activity[Ref.29614317] HC50=33.74μg/mL against human red blood cells
Cytotoxicity[Ref.29614318] No cytotoxicity information found
N-terminal ModificationAcylation (Gly1 conjugated with a palmitoyl group)
C-terminal ModificationAmidation
Linear/Cyclic/BranchedLinear
Uniprot
PDB
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PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID29614317

Physicochemical Properties

Residues8
SequenceGLLKRIKT
Molecular Weight928.174
Grand Average of Hydropathy-0.163
Isoelectric Point11.166
Charge at pH 7.42.552
Secondary StructureHelix: 0.375, Turn: 0.125, Sheet: 0.250
Instability Index28.275
Aromaticity0

Similar Structure Search

Candidates based on structure

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