Basic Information
| ID | DRAMP20922 |
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| Sequence | GIHDILKYGAPS |
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| Length | 12 |
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| Name | Myxinidin (K10) |
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| Source | Synthetic construct |
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| Activity | Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram- |
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| Pathogen | [Ref.24957834] Gram-negative bacteria: Escherichia coli (MIC =15 microM), Pseudomonas aeruginosa (MIC >50 microM), S. Salmonella typhimurium (MIC >50 microM), Klebsiella pneumoniae (MIC =10 microM) ;## Gram-positive bacteria: Staphylococcus aureus (MIC =20 microM) |
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| Hemolytic Activity | [Ref.24957834] Some peptides at 50 μM led to about 10% hemolysis against human red blood cells, but in general, negligible hemolytic activity is observed even at 100 μM and 200 μM peptide. |
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| Cytotoxicity | [Ref.24957834] The toxicity of the peptide against Vero cells is 0.7%, 0.7%, 2%, 7% and 12% at peptide concentrations of 1, 20, 50, 100 and 200 μM. |
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| N-terminal Modification | Free |
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| C-terminal Modification | Amidation |
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| Linear/Cyclic/Branched | Linear |
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| Uniprot |
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| PDB |
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| 3D View | |
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| PDB Download | Download PDB Predicted by Alphafold2 |
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| PubMed ID | 24957834 |
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