Basic Information

IDDRAMP20977
SequenceWLLKRWKKLL
Length10
NameAnoplin-1 (Derived from Anoplin)
SourceSynthetic construct
ActivityAntimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-
Pathogen[Ref.25316570]Gram-positive bacteria : Staphylococcus aureus (MIC=32 μg/ml), bacillus subtilis (MIC=16 μg/ml);##Gram-negative bacteria : Escherichia coli (MIC=64 μg/ml), Peudomonas eruginosa (MIC=8 μg/ml)
Hemolytic Activity[Ref.25316570] 0% hemolysis at 100 μg/ml , 1% hemolysis at 200 μg/ml against mice red blood cells
Cytotoxicity[Ref.25316570] No cytotoxicity information found
N-terminal ModificationFree
C-terminal ModificationAmidation
Linear/Cyclic/BranchedLinear
Uniprot
PDB
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID25316570

Physicochemical Properties

Residues10
SequenceWLLKRWKKLL
Molecular Weight1383.768
Grand Average of Hydropathy-0.28
Isoelectric Point11.264
Charge at pH 7.43.55
Secondary StructureHelix: 0.600, Turn: 0.000, Sheet: 0.400
Instability Index94.24
Aromaticity0.2

Similar Structure Search

Candidates based on structure

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