Basic Information

IDDRAMP04177
SequenceLKWLKKWLK
Length9
NameL3K4W2 (LlKmW2 model peptides)
SourceSynthetic construct (De novo design)
ActivityAntimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-
PathogenGram-positive bacteria: B. subtilis (MIC=40 µg/ml), S. aureus (MIC=10 µg/ml), S. epidermis (MIC=40 µg/ml), M. luteus (MIC=80 µg/ml), S. aureus (MRSA) (MIC>80 µg/ml).##Gram-negative bacteria: E. coli (MIC=40 µg/ml), S. dysentariae (MIC>80 µg/ml), S. typhimorium (MIC>80 µg/ml), K. pneumoniae (MIC>80 µg/ml), P. aeruginosa (MIC=80 µg/ml).
Hemolytic ActivityNo hemolysis information or data found in the reference(s) presented in this entry
CytotoxicityNot included yet
N-terminal ModificationNot included yet
C-terminal ModificationNot included yet
Linear/Cyclic/BranchedNot included yet
Uniprot
PDB
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID20736034

Physicochemical Properties

Residues9
SequenceLKWLKKWLK
Molecular Weight1242.597
Grand Average of Hydropathy-0.667
Isoelectric Point10.478
Charge at pH 7.43.547
Secondary StructureHelix: 0.556, Turn: 0.000, Sheet: 0.333
Instability Index8.011
Aromaticity0.222

Similar Structure Search

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