| ID | DRAMP03990 |
|---|---|
| Sequence | LLKWLKKL |
| Length | 8 |
| Name | L4K3W4 (LlKmWn model peptide) |
| Source | Synthetic construct (De novo design) |
| Activity | Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram- |
| Pathogen | Gram-positive bacteria: Bacillus subtilis ATCC 6633 (MIC=50 µg/ml), Staphylococcus aureus ATCC 6538p (MIC=25 µg/ml);##Gram-negative bacterium: Pseudomonas aeruginosa ATCC 27853 (MIC=50 µg/ml). |
| Hemolytic Activity | No hemolysis information or data found in the reference(s) presented in this entry |
| Cytotoxicity | Not included yet |
| N-terminal Modification | Not included yet |
| C-terminal Modification | Not included yet |
| Linear/Cyclic/Branched | Not included yet |
| Uniprot | |
| PDB | |
| 3D View | |
| PDB Download | Download PDB Predicted by Alphafold2 |
| PubMed ID | 19544481 |
Physicochemical Properties
| Residues | 8 |
|---|---|
| Sequence | LLKWLKKL |
| Molecular Weight | 1041.373 |
| Grand Average of Hydropathy | 0.325 |
| Isoelectric Point | 10.302 |
| Charge at pH 7.4 | 2.55 |
| Secondary Structure | Helix: 0.625, Turn: 0.000, Sheet: 0.500 |
| Instability Index | -7.663 |
| Aromaticity | 0.125 |