Basic Information

IDDRAMP04179
SequenceLKWLLKWLL
Length9
NameL5K2W2 (LlKmW2 model peptides)
SourceSynthetic construct (De novo design)
ActivityAntimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-
PathogenGram-positive bacteria: B. subtilis (MIC<1.3 µg/ml), S. aureus (MIC<1.3 µg/ml), S. epidermis (MIC<1.3 µg/ml), M. luteus (MIC=2.5 µg/ml), S. aureus (MRSA) (MIC=2.5 µg/ml).##Gram-negative bacteria: E. coli (MIC=5 µg/ml), S. dysentariae (MIC=2.5 µg/ml), S. typhimorium (MIC=10 µg/ml), K. pneumoniae (MIC=5 µg/ml), P. aeruginosa (MIC=10 µg/ml).
Hemolytic ActivityNo hemolysis information or data found in the reference(s) presented in this entry
CytotoxicityNot included yet
N-terminal ModificationNot included yet
C-terminal ModificationNot included yet
Linear/Cyclic/BranchedNot included yet
Uniprot
PDB
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID20736034

Physicochemical Properties

Residues9
SequenceLKWLLKWLL
Molecular Weight1212.568
Grand Average of Hydropathy1.044
Isoelectric Point10.003
Charge at pH 7.41.552
Secondary StructureHelix: 0.778, Turn: 0.000, Sheet: 0.556
Instability Index17.444
Aromaticity0.222

Similar Structure Search

Candidates based on structure

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