Basic Information

IDDRAMP20980
Sequencekllkwwkkll
Length10
NameAnoplin-4 (Derived from Anoplin)
SourceSynthetic construct
ActivityAntimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-
Pathogen[Ref.25316570]Gram-positive bacteria : Staphylococcus aureus (MIC=8 μg/ml), bacillus subtilis (MIC=4 μg/ml);##Gram-negative bacteria : Escherichia coli (MIC=8 μg/ml), Peudomonas eruginosa (MIC=8 μg/ml)
Hemolytic Activity[Ref.25316570] 0.5% hemolysis at 12.5 μg/ml , 0.5% hemolysis at 25 μg/ml , 2% hemolysis at 50 μg/ml , 1% hemolysis at 100 μg/ml , 4% hemolysis at 200 μg/ml against mice red blood cells
Cytotoxicity[Ref.25316570] No cytotoxicity information found
N-terminal ModificationFree
C-terminal ModificationAmidation
Linear/Cyclic/BranchedLinear
Uniprot
PDB
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID25316570

Physicochemical Properties

Residues10
Sequencekllkwwkkll
Molecular Weight1355.755
Grand Average of Hydropathy-0.22
Isoelectric Point10.478
Charge at pH 7.43.547
Secondary StructureHelix: 0.600, Turn: 0.000, Sheet: 0.400
Instability Index-16.47
Aromaticity0.2

Similar Structure Search

Candidates based on structure

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