Basic Information

IDDRAMP04182
SequenceLLKWLLKWLKK
Length11
NameL5K4W2 (LlKmW2 model peptides)
SourceSynthetic construct (De novo design)
ActivityAntimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-
PathogenGram-positive bacteria: B. subtilis (MIC<1.3 µg/ml), S. aureus (MIC<1.3 µg/ml), S. epidermis (MIC<1.3 µg/ml), M. luteus (MIC<1.3 µg/ml), S. aureus (MRSA) (MIC=5 µg/ml).##Gram-negative bacteria: E. coli (MIC=10 µg/ml), S. dysentariae (MIC=10 µg/ml), S. typhimorium (MIC=20 µg/ml), K. pneumoniae (MIC=20 µg/ml), P. aeruginosa (MIC=10 µg/ml).
Hemolytic ActivityNo hemolysis information or data found in the reference(s) presented in this entry
CytotoxicityNot included yet
N-terminal ModificationNot included yet
C-terminal ModificationNot included yet
Linear/Cyclic/BranchedNot included yet
Uniprot
PDB
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID20736034

Physicochemical Properties

Residues11
SequenceLLKWLLKWLKK
Molecular Weight1468.912
Grand Average of Hydropathy0.145
Isoelectric Point10.478
Charge at pH 7.43.547
Secondary StructureHelix: 0.636, Turn: 0.000, Sheet: 0.455
Instability Index8.373
Aromaticity0.182

Similar Structure Search

Candidates based on structure

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