Basic Information

IDDRAMP04183
SequenceLLKWLLKWLLK
Length11
NameL6K3W2 (LlKmW2 model peptides)
SourceSynthetic construct (De novo design)
ActivityAntimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-
PathogenGram-positive bacteria: B. subtilis (MIC<1.3 µg/ml), S. aureus (MIC=2.5 µg/ml), S. epidermis (MIC<1.3 µg/ml), M. luteus (MIC=2.5 µg/ml), S. aureus (MRSA) (MIC=5 µg/ml).##Gram-negative bacteria: E. coli (MIC>80 µg/ml), S. dysentariae (MIC>80 µg/ml), S. typhimorium (MIC>80 µg/ml), K. pneumoniae (MIC>80 µg/ml), P. aeruginosa (MIC>80 µg/ml).
Hemolytic ActivityNo hemolysis information or data found in the reference(s) presented in this entry
CytotoxicityNot included yet
N-terminal ModificationNot included yet
C-terminal ModificationNot included yet
Linear/Cyclic/BranchedNot included yet
Uniprot
PDB
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID20736034

Physicochemical Properties

Residues11
SequenceLLKWLLKWLLK
Molecular Weight1453.898
Grand Average of Hydropathy0.845
Isoelectric Point10.302
Charge at pH 7.42.55
Secondary StructureHelix: 0.727, Turn: 0.000, Sheet: 0.545
Instability Index8.373
Aromaticity0.182

Similar Structure Search

Candidates based on structure

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