Basic Information

IDDRAMP04189
SequenceLLKWLKKLLKK
Length11
NameL5K5W4 (L5K5Wn model peptide)
SourceSynthetic construct (De novo design)
ActivityAntimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-
PathogenGram-positive bacteria: Bacillus subtilis ATCC 6633 (MIC=2 µg/mL), Staphylococcus aureus ATCC 6538p (MIC=2 µg/mL), Staphylococcus epidermis ATCC 12228 (MIC=2 µg/mL), Micrococcus luteus ATCC 10240 (MIC=4 µg/mL), MRSA-TK784 (MIC=16 µg/mL).##Gram-negative bacteria: Escherichia coli ATCC 25922 (MIC=4 µg/mL), Shigella dysenteriae ATCC 9752 (MIC=2 µg/mL), Salmonella typhimurium ATCC 14028 (MIC=4 µg/mL), Klebsiella pneumoniae ATCC 10031 (MIC=4 µg/mL), Pseudomonas aeruginosa ATCC 27853 (MIC=4 µg/mL).
Hemolytic ActivityNo hemolysis information or data found in the reference(s) presented in this entry
CytotoxicityNot included yet
N-terminal ModificationNot included yet
C-terminal ModificationNot included yet
Linear/Cyclic/BranchedNot included yet
Uniprot
PDB
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID23344198

Physicochemical Properties

Residues11
SequenceLLKWLKKLLKK
Molecular Weight1410.875
Grand Average of Hydropathy-0.127
Isoelectric Point10.602
Charge at pH 7.44.545
Secondary StructureHelix: 0.545, Turn: 0.000, Sheet: 0.455
Instability Index-10.564
Aromaticity0.091

Similar Structure Search

Candidates based on structure

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