Basic Information

IDDRAMP03994
SequenceKKLLKWLLKLL
Length11
NameL6K4W6 (LlKmWn model peptide)
SourceSynthetic construct (De novo design)
ActivityAntimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-
PathogenGram-positive bacteria: Bacillus subtilis ATCC 6633 (MIC=1.6 µg/ml), Staphylococcus aureus ATCC 6538p (MIC=1.6 µg/ml), Staphylococcus epidermis ATCC 12228 (MIC=1.6 µg/ml), Micrococcus luteus ATCC 10240 (MIC=1.6 µg/ml);##Gram-negative bacteria: Escherichia coli ATCC 25922 (MIC=6.3 µg/ml), Shigella dysentariae ATCC 9752 (MIC=3.1 µg/ml), Salmonella typhomurium ATCC 14028 (MIC=25 µg/ml), Klebsiella pneumoniae ATCC 10031 (MIC=3.1 µg/ml), Pseudomonas aeruginosa ATCC 27 853 (MIC=50 µg/ml).
Hemolytic ActivityNo hemolysis information or data found in the reference(s) presented in this entry
CytotoxicityNot included yet
N-terminal ModificationNot included yet
C-terminal ModificationNot included yet
Linear/Cyclic/BranchedNot included yet
Uniprot
PDB
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID19544481

Physicochemical Properties

Residues11
SequenceKKLLKWLLKLL
Molecular Weight1395.86
Grand Average of Hydropathy0.573
Isoelectric Point10.478
Charge at pH 7.43.547
Secondary StructureHelix: 0.636, Turn: 0.000, Sheet: 0.545
Instability Index-10.564
Aromaticity0.091

Similar Structure Search

Candidates based on structure

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