Basic Information

IDDRAMP03995
SequenceLKLLKWLLKLL
Length11
NameL7K3W6 (LlKmWn model peptide)
SourceSynthetic construct (De novo design)
ActivityAntimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-
PathogenGram-positive bacteria: Bacillus subtilis ATCC 6633 (MIC=1.6 µg/ml), Staphylococcus aureus ATCC 6538p (MIC=3.1 µg/ml), Staphylococcus epidermis ATCC 12228 (MIC=3.1 µg/ml), Micrococcus luteus ATCC 10240 (MIC=3.1 µg/ml);##Gram-negative bacteria: Escherichia coli ATCC 25922 (MIC=50 µg/ml), Shigella dysentariae ATCC 9752 (MIC=12.5 µg/ml), Klebsiella pneumoniae ATCC 10031 (MIC=50 µg/ml).
Hemolytic ActivityNo hemolysis information or data found in the reference(s) presented in this entry
CytotoxicityNot included yet
N-terminal ModificationNot included yet
C-terminal ModificationNot included yet
Linear/Cyclic/BranchedNot included yet
Uniprot
PDB
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID19544481

Physicochemical Properties

Residues11
SequenceLKLLKWLLKLL
Molecular Weight1380.845
Grand Average of Hydropathy1.273
Isoelectric Point10.302
Charge at pH 7.42.55
Secondary StructureHelix: 0.727, Turn: 0.000, Sheet: 0.636
Instability Index-18.282
Aromaticity0.091

Similar Structure Search

Candidates based on structure

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