Basic Information
| ID | DRAMP21035 |
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| Sequence | KAAKAAKKAAKAAWK |
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| Length | 15 |
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| Name | AC-UM-14W (De novo synthesis) |
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| Source | Synthetic construct |
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| Activity | Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram- |
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| Pathogen | [Ref.26235946]Gram-positive bacteria : Bacillus subtilis (MIC>200 μg/ml), Staphylococcus aureus (MIC>200 μg/ml), Staphylococcus epidermis (MIC>200 μg/ml);##Gram-negative bacteria : Escherichia coli (MIC>200 μg/ml), Shigella dysentariae (MIC>200 μg/ml), Salmonella typhimurium (MIC>200 μg/ml), Klebsiella pneumonia (MIC>200 μg/ml), Pseudomonas aeruginosa (MIC>200 μg/ml) |
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| Hemolytic Activity | [Ref.26235946] <1% hemolysis at 12.5 μM , <1% hemolysis at 25 μM against human red blood cells |
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| Cytotoxicity | [Ref.26235946] No cytotoxic information found. |
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| N-terminal Modification | Acylation (Conjugated with acetyl group) |
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| C-terminal Modification | Amidation |
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| Linear/Cyclic/Branched | Linear |
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| Uniprot |
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| PDB |
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| 3D View | |
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| PDB Download | Download PDB Predicted by Alphafold2 |
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| PubMed ID | 26235946 |
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