Basic Information

IDDRAMP21104
SequenceGIGGALLNVGKVALKGLAKGLAEHFAN
Length27
NameFeleucin-2 (toads, amphibians, animals)
SourceBombina variegata (Yellow-bellied toad)
ActivityAntimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal
Pathogen[Ref.25003126] Gram-positive bacteria : Staphylococcus aureus(MIC=8 mg/L, MBC=32 mg/L);##Gram-negative bacteria : Escherichia coli(MIC=32 mg/L, MBC=32 mg/L);##Fungi : Candida albicans(MIC=32 mg/L, MBC=32 mg/L)
Hemolytic Activity[Ref.25003126] 100% hemolysis at 64 mg/L against horse red blood cells
Cytotoxicity[Ref.25003126] No cytotoxicity information found
N-terminal ModificationFree
C-terminal ModificationAmidation
Linear/Cyclic/BranchedLinear
Uniprot X5JB11 
PDB
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PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID25003126

Physicochemical Properties

Residues27
SequenceGIGGALLNVGKVALKGLAKGLAEHFAN
Molecular Weight2619.069
Grand Average of Hydropathy0.589
Isoelectric Point9.703
Charge at pH 7.41.588
Secondary StructureHelix: 0.333, Turn: 0.296, Sheet: 0.407
Instability Index-17.589
Aromaticity0.037

Similar Structure Search

Candidates based on structure

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