Basic Information

IDDRAMP21107
SequenceFLGLLGSLL
Length9
NameFeleucin-BO1 (toads, amphibians, animals)
SourceAsian bombinid toad species, Bombina orientalis
ActivityAntimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal
Pathogen[Ref.25056849] Gram-positive bacteria : Staphylococcus aureus(MIC=3 μM, MBC=6 μM);##Gram-negative bacteria : Escherichia coli(MIC=12 μM, MBC=25 μM);##Fungi : Candida albicans(MIC=6 μM, MBC=12 μM)
Hemolytic Activity[Ref.25056849] 100% hemolysis at 80 mg/L against horse red blood cells
Cytotoxicity[Ref.25056849] No cytotoxicity information found
N-terminal ModificationFree
C-terminal ModificationAmidation
Linear/Cyclic/BranchedLinear
Uniprot
PDB
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PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID25056849

Physicochemical Properties

Residues9
SequenceFLGLLGSLL
Molecular Weight932.157
Grand Average of Hydropathy2.244
Isoelectric Point5.525
Charge at pH 7.4-0.443
Secondary StructureHelix: 0.667, Turn: 0.333, Sheet: 0.556
Instability Index8.889
Aromaticity0.111

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