Basic Information
| ID | DRAMP21116 |
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| Sequence | KWCFRVCSRGICYRRCR |
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| Length | 17 |
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| Name | Y8S (Derived from tachyplesin I) |
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| Source | Synthetic construct |
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| Activity | Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram- |
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| Pathogen | [Ref.26549611] Gram-positive bacteria : Staphylococcus aureus 209P(MIC=3.13 μM);##Gram-negative bacteria : Escherichia coli C600(MIC=0.8 μM), Pseudomonas aeruginosa PAO1(MIC=3.13 μM) |
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| Hemolytic Activity | [Ref.26549611] MHC2=310 μM against human red blood cells |
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| Cytotoxicity | [Ref.26549611] The cell viability of human embryonic fibroblasts HEF is 100%, 92.9%, 87.1%, 72.9%, 60.0% and 45.0% at peptide concentrations of 0, 6.25, 12.5, 25, 50 and 100 μM. |
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| N-terminal Modification | Free |
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| C-terminal Modification | Amidation |
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| Linear/Cyclic/Branched | Linear |
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| Uniprot |
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| PDB |
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| 3D View | |
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| PDB Download | Download PDB Predicted by Alphafold2 |
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| PubMed ID | 26549611 |
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