Basic Information

IDDRAMP21139
SequenceRLLRPLLQLLKQKLR
Length15
NameGNU7 (De novo synthesis)
SourceSynthetic construct
ActivityAntimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal
Pathogen[Ref.23946320] Gram-positive bacteria : Bacillus subtilis(MIC=2 mg/L), Enterococcus faecalis(MIC=2 mg/L), Micrococcus luteus(MIC=2 mg/L), Staphylococcus aureus(MIC=2 mg/L);##Gram-negative bacteria : Escherichia coli(MIC=2 mg/L), Pseudomonas aeruginosa(MIC=2 mg/L), Salmonella typhimurium(MIC=2 mg/L);##Fungi : Candida albicans(MIC=2 mg/L), Cryptococcus neoformans(MIC=2 mg/L), Saccharomyces cerevisiae(MIC=4 mg/L)
Hemolytic Activity[Ref.23946320] 0% hemolysis at 140 mg/L against human red blood cells
Cytotoxicity[Ref.23946320] The cell viability of hPBMCs is at peptide concentrations of 4, 8, 16, 32, 64 μg/ml
N-terminal ModificationFree
C-terminal ModificationFree
Linear/Cyclic/BranchedLinear
Uniprot
PDB
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID23946320

Physicochemical Properties

Residues15
SequenceRLLRPLLQLLKQKLR
Molecular Weight1888.394
Grand Average of Hydropathy-0.22
Isoelectric Point12
Charge at pH 7.44.552
Secondary StructureHelix: 0.467, Turn: 0.067, Sheet: 0.467
Instability Index74.027
Aromaticity0

Similar Structure Search

Candidates based on structure

Address: No.2699 Qianjin Street, Changchun City, China. Zip Code: 130012. 苏ICP备2021057230号-1.