Basic Information

IDDRAMP21167
Sequencegilssllkklkkiiak
Length16
NameHYL-13 (Derived from HYL)
SourceSynthetic construct
ActivityAntimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal
Pathogen[Ref.26998557] Gram-positive bacteria : Staphylococcus aureus 6271(MIC=5.7 μM), Staphylococcus epidermidis(MIC=3.2 μM);##Gram-negative bacteria : Escherichia coli(MIC=4.5 μM), Pseudomonas aeruginosa 5482(MIC=4.5 μM);##Fungi : Candida albicans(MIC=9 μM)
Hemolytic Activity[Ref.26998557] LC50=333 μM against human red blood cells
Cytotoxicity[Ref.26998557] No cytotoxicity information found.
N-terminal ModificationFree
C-terminal ModificationAmidation
Linear/Cyclic/BranchedLinear
Uniprot
PDB
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID26998557

Physicochemical Properties

Residues16
Sequencegilssllkklkkiiak
Molecular Weight1753.264
Grand Average of Hydropathy0.562
Isoelectric Point10.602
Charge at pH 7.44.545
Secondary StructureHelix: 0.438, Turn: 0.188, Sheet: 0.312
Instability Index6.919
Aromaticity0

Similar Structure Search

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