Basic Information
| ID | DRAMP21243 |
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| Sequence | GFFALIPKIISSPLFKTLLSAVGSALS |
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| Length | 27 |
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| Name | pardaxin-6 (GE-6) (Derived from pardaxin) |
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| Source | Synthetic construct |
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| Activity | Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram- |
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| Pathogen | [Ref.23598079] Gram-positive bacteria : Micrococcus luteus(MIC=25 mg/L), Staphylococcus aureus(MIC=50 mg/L), Streptococcus pneumoniae(MIC=50 mg/L), Streptococcus agalactiae(MIC=50 mg/L), Staphylococcus sp.(MIC=6.25 mg/L);##Gram-negative bacteria : Grouper Vibrio alginolyticus(MIC=12.5 mg/L), Vibrio harveyi(MIC=12.5 mg/L), Vibrio vulnificus(MIC=50 mg/L) |
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| Hemolytic Activity | [Ref.23598079] 8% hemolysis at 12.5 mg/L , 29% hemolysis at 25 mg/L , 38% hemolysis at 50 mg/L , 57.5% hemolysis at 100 mg/L , 99% hemolysis at 200 mg/L , 98% hemolysis at 400 mg/L against sheep red blood cells |
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| Cytotoxicity | [Ref.23598079] No cytotoxicity information found. |
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| N-terminal Modification | Free |
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| C-terminal Modification | Free |
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| Linear/Cyclic/Branched | Linear |
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| Uniprot |
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| PDB |
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| 3D View | |
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| PDB Download | Download PDB Predicted by Alphafold2 |
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| PubMed ID | 23598079 |
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