Basic Information

IDDRAMP21365
SequenceKALKKFLKAWAKLFKAL
Length17
Name1Kamp-4L (De Novo Synthesis)
Sourcesynthetic construct
ActivityAntimicrobial, Antibacterial, Anti-Gram-
Pathogen[Ref.31194548] Gram-negative Bacteria: Escherichia coli K12 (MIC=1.6μM), Pseudomonas aeruginosa PAO1(MIC=3.1μM), Pseudomonas aeruginosa PA214(MIC=3.1μM), Pseudomonas aeruginosa PA287(MIC=3.1μM), Pseudomonas aeruginosa PA330(MIC=6.3μM), Pseudomonas aeruginosa PA380(MIC=6.3μM)
Hemolytic Activity[Ref.31194548] 81% (± 9.4) hemolysis at 40μM against human blood cells.
Cytotoxicity[Ref.31194548] No cytotoxicity information found
N-terminal ModificationFree
C-terminal ModificationAmidation
Linear/Cyclic/BranchedLinear
Uniprot
PDB
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID31194548

Physicochemical Properties

Residues17
SequenceKALKKFLKAWAKLFKAL
Molecular Weight2004.549
Grand Average of Hydropathy0.218
Isoelectric Point10.699
Charge at pH 7.45.542
Secondary StructureHelix: 0.412, Turn: 0.000, Sheet: 0.471
Instability Index-23.253
Aromaticity0.176

Similar Structure Search

Candidates based on structure

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