ABPDB

Basic Information

ID	DRAMP20826
Sequence	GLFKKLRRKIKKGFKKIFKRL
Length	21
Name	AM-CATH21
Source	Synthetic construct
Activity	Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-
Pathogen	[Ref.28089718] Gram-positive bacteria: Staphylococcus aureus ATCC 25923 (MIC=28μg/ml), Staphylococcus aureus ATCC 33592 (MIC=28μg/ml);##Gram-negative bacteria:Acinetobacter baumannii ATCC 9955 (MIC=42μg/ml), Acinetobacter baumannii ATCC BAA-1794 (MIC=10μg/ml), Escherichia coli ATCC 4157 (MIC=21μg/ml), Escherichia coli ATCC 51659 (MIC=140μg/ml), K. pneumoniae ATCC 33495 (MIC=5.2μg/ml), K. pneumoniae ATCC BAA-1705 (MIC=28μg/ml), Pseudomonas aeruginosa ATCC 9027 (MIC=10μg/ml), Pseudomonas aeruginosa ATCC BAA-2110 (MIC=42μg/ml)
Hemolytic Activity	[Ref.28089718] 0.5% hemolysis at 300μg/ml against sheep red cells
Cytotoxicity	[Ref.28089718] The survival rate of A549 human lung epithelial cells is 113% at a peptide concentration of 300 μg/ml
N-terminal Modification	Free
C-terminal Modification	Free
Linear/Cyclic/Branched	Linear
Uniprot
PDB
3D View
PDB Download	Download PDB Predicted by Alphafold2
PubMed ID	28089718

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