Basic Information
| ID | DRAMP20936 |
| Sequence | RVKRFKKFFRKIKKGFRKIFKKTKIFIG |
| Length | 28 |
| Name | ΔPb-CATH1 |
| Source | Synthetic construct |
| Activity | Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram- |
| Pathogen | [Ref.28630199] Gram-positive bacteria: Staphylococcus aureus (ATCC 29213)(MIC>128 μg/ml); B. cereus ATCC 10876 (MIC=46 μg/ml);##Gram-negative bacteria: Escherichia coli ATCC 25922 (MIC=2 μg/ml), Pseudomonas aeruginosa ATCC 27853 (MIC=3 μg/ml), S. typhimurium ATCC 14028 (MIC=1.5 μg/ml) |
| Hemolytic Activity | [Ref.28630199]1.4 ± 0.4% hemolysis at 8 μg/ml, 5.1 ± 0.5% hemolysis at 16 μg/ml, 7.3 ± 0.6% hemolysis at 32 μg/ml, 12.2 ± 0.7% hemolysis at 64 μg/ml against chicken red blood cells |
| Cytotoxicity | [Ref.28630199] No cytotoxicity information found |
| N-terminal Modification | Free |
| C-terminal Modification | Free |
| Linear/Cyclic/Branched | Linear |
| Uniprot |
|
| PDB |
|
| 3D View | |
|---|
| PDB Download | Download PDB Predicted by Alphafold2 |
|---|
| PubMed ID | 28630199 |
|---|