ABPDB

Basic Information

ID	DRAMP21406
Sequence	Gkiiklkaslkll
Length	13
Name	DGL13K (De Novo Synthesis)
Source	synthetic construct
Activity	Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-
Pathogen	[Ref.31071184] Gram-positive bacteria:Staphylococcus aureus Xen36(MIC=2.6μg/ml), Staphylococcus aureus USA300(MIC=5.2μg/ml);##Gram-negative bacteria: Pseudomonas aeruginosa (MIC=5.2μg/ml)
Hemolytic Activity	[Ref.31071184] LD50=950μg/ml against human blood cells
Cytotoxicity	[Ref.31071184] The cytotoxicity of D-GL13K on HEK cells is 1.5%, 0.9%, 2.1%, 1.5%, 34.2%, 32.4% and 41.1% at peptide concentrations of 1, 3.9, 15.6, 62.5, 250 and 1000 μg/mL, while the cytotoxicity of PMX on HEK cells (Control samples) is 1.2%, 1.2%, 6.6%, 3.6%, 39.6%, 47.1% and 68.5% at peptide concentrations of 1, 3.9, 15.6, 62.5, 250 and 1000 μg/mL.
N-terminal Modification	Free
C-terminal Modification	Amidation
Linear/Cyclic/Branched	Linear
Uniprot
PDB
3D View
PDB Download	Download PDB Predicted by Alphafold2
PubMed ID	31071184

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